immunological tolerance

immunological tolerance
Tolerance Tol"er*ance, n. [L. tolerantia: cf. F. tol['e]rance.] 1. The power or capacity of enduring; the act of enduring; endurance. [1913 Webster]

Diogenes, one frosty morning, came into the market place, shaking, to show his tolerance. --Bacon. [1913 Webster]

2. The endurance of the presence or actions of objectionable persons, or of the expression of offensive opinions; toleration. [1913 Webster]

3. (Med.) The power possessed or acquired by some persons of bearing doses of medicine which in ordinary cases would prove injurious or fatal. [1913 Webster]

4. (Forestry) Capability of growth in more or less shade. [Webster 1913 Suppl.]

5. the allowed amount of variation from the standard or from exact conformity to the specified dimensions, weight, hardness, voltage etc., in various mechanical or electrical devices or operations; -- caklled also {allowance} specif.: (Coinage) The amount which coins, either singly or in lots, are legally allowed to vary above or below the standard of weight or fineness. [Webster 1913 Suppl. +PJC]

6. (Biochemistry) the capacity to resist the deleterious action of a chemical agent normally harmful to the organism; as, the acquired tolerance of bacteria to anitbiotics. [PJC]

7. (Immunology) the acquired inability to respond with an immune reaction to an antigen to which the organism normally responds; -- called also {immunotolerance}, {immunological tolerance}, or {immune tolerance}. Such tolerance may be induced by exposing an animal to the antigen at a very early stage of life, prior to maturation of the immune system, or, in adults, by exposing the animal to repeated low doses of a weak protein antigen ({low-zone tolerance}), or to a large amount of an antigen ({high-zone tolerance}). [PJC]

{Tolerance of the mint}. (Coinage) Same as {Remedy of the mint}. See under {Remedy}. [1913 Webster]


The Collaborative International Dictionary of English. 2000.

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Look at other dictionaries:

  • immunological tolerance — immunological tolerance. См. иммунологическая толерантность. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • immunological tolerance — noun The failure of the body to recognize antigens with consequent absence of antibody production • • • Main Entry: ↑immune …   Useful english dictionary

  • immunological tolerance — Specific unresponsiveness to antigen. Self tolerance is a process occurring normally early in life due to suppression of self reactive lymphocyte clones. Tolerance to foreign antigens can be induced in adult life by exposure to antigens under… …   Dictionary of molecular biology

  • immunological tolerance — a failure of the body to distinguish between materials that are self , and therefore to be tolerated, and those that are not self , against which it mounts an immune response. Tolerance results from the interaction of antigens with lymphocytes… …   Medical dictionary

  • immunological tolerance — a failure of the body to distinguish between materials that are ‘self’, and therefore to be tolerated, and those that are ‘not self’, against which it mounts an immune response. Tolerance results from the interaction of antigens with lymphocytes… …   The new mediacal dictionary

  • Tolerance — Tol er*ance, n. [L. tolerantia: cf. F. tol[ e]rance.] 1. The power or capacity of enduring; the act of enduring; endurance. [1913 Webster] Diogenes, one frosty morning, came into the market place, shaking, to show his tolerance. Bacon. [1913… …   The Collaborative International Dictionary of English

  • Tolerance of the mint — Tolerance Tol er*ance, n. [L. tolerantia: cf. F. tol[ e]rance.] 1. The power or capacity of enduring; the act of enduring; endurance. [1913 Webster] Diogenes, one frosty morning, came into the market place, shaking, to show his tolerance. Bacon.… …   The Collaborative International Dictionary of English

  • tolerance — 1. The ability to endure or be less responsive to a stimulus, especially over a period of continued exposure. 2. The power of resisting the action of a poison or of taking a drug continuously or in large doses without injurious effects. [L.… …   Medical dictionary

  • tolerance — n. the reduction or loss of the normal response to a drug or other substance that usually provokes a reaction in the body. Drug tolerance may develop after taking a particular drug over a long period of time. In such cases increased doses are… …   The new mediacal dictionary

  • immunological memory — The systems responsible for the situation where reactions to a second or subsequent exposure to an antigen are more extensive than those seen on first exposure (but see also immunological tolerance. The memory is best explained by clonal… …   Dictionary of molecular biology

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