Down's syndrome

Down's syndrome
Down syndrome Down" syn`drome, Down's syndrome Down's" syn`drome, n. (Med.) A congenital disorder caused by an extra chromosome 21 in some or all cells. It causes a variable number and degree of abnormalities, including retarded growth, mental retardation, a short nose, prominent epicanthic folds on the eyelids, a protruding lower lip, and other physical features having varying degrees of deviation from the normal. Called also {mongolism}, {trisomy-21} and {trisomy 21 syndrome}. [PJC]

The Collaborative International Dictionary of English. 2000.

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  • Down's syndrome — Down syndrome a condition resulting from a chromosomal abnormality most commonly due to the presence of three copies of chromosome 21 (trisomy 21), which is most likely to occur with advanced maternal age. Down s syndrome can also occur as a… …   The new mediacal dictionary

  • Down's syndrome — ► NOUN Medicine ▪ a congenital disorder causing intellectual impairment and physical abnormalities. USAGE Down s syndrome is the accepted term in modern use, and former terms such as mongol and mongolism, which are likely to cause offence, should …   English terms dictionary

  • Down's syndrome — Down s ,syndrome noun uncount DOWN SYNDROME …   Usage of the words and phrases in modern English

  • Down's syndrome — Down s .syndrome n [U] [Date: 1900 2000; Origin: J. H. L. Down (1828 96), English doctor] a condition that someone is born with, that stops them from developing in a normal way, both mentally and physically …   Dictionary of contemporary English

  • Down's Syndrome — 1961, from J.L.H. Down (1828 1896), English physician; chosen as a less racist name for the condition than earlier MONGOLISM (Cf. mongolism) …   Etymology dictionary

  • Down's syndrome — N UNCOUNT Down s syndrome is a disorder that some people are born with. People who have Down s syndrome have a flat forehead and sloping eyes and lower than average intelligence. (in AM, usually use Down syndrome) …   English dictionary

  • Down's syndrome — a condition resulting from a genetic abnormality in which an extra chromosome is present (there are three no. 21 chromosomes instead of the usual two), giving a total of 47 chromosomes rather than the normal 46. The chances of having a Down s… …   Medical dictionary

  • Down's syndrome —    a congenital disorder due to a chromosome deficiency    This is an example of a phrase incorporating syndrome being used to avoid a taboo word in this case what was formerly known as Mongolism. Here the stigma and the possible racial sneer are …   How not to say what you mean: A dictionary of euphemisms

  • Down's syndrome — noun Medicine a congenital disorder causing intellectual impairment and physical abnormalities including short stature and a broad facial profile. Origin 1960s: named after the 19th cent. English physician John L. H. Down. Usage Of relatively… …   English new terms dictionary

  • Down's syndrome — UK [ˈdaʊnz ˌsɪndrəʊm] / US [ˈdaʊnz ˌsɪndroʊm] noun [uncountable] medical a medical condition that someone is born with, that makes them develop in a different way from most people, mentally and physically. Down s syndrome is often simply called… …   English dictionary

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