Cephalosporin Ceph"a*lo*spor`in (s[e^]f"[.a]*l[-o]*sp[=o]r`[i^]n), n. [from Cephalosporium, a fungus producing the first of the series discovered.] (Chem.) any of a class of chemical substances, some of which have therapeutically useful antibacterial activity, whose structure contains a beta-lactam ring fused to a six-membered ring containing a sulfur and a nitrogen atom. The first of the series, {cephalosporin C}, was discovered by G. Brotzu in 1955 in the culture broth of a {Cephalosporium} species found off the coast of Sardinia. Other cephalosporins have been found to be produced by species of soil bacteria (actinomycetes). Many semisynthetic analogs have been tested for antibacterial effect, and several of them have found use as important clinically useful antibacterial agents, some of which may be taken orally for treatment of bacterial infections. The cephalosporins are the second class of beta-lactam antibiotic to be discovered, the first being the {penicillins} and more recent classes being the {thienamycins} and {sulfazecins}. The {cephamycins} are a variant of cephalosporins with a methoxyl group on the beta-lactam ring, rendering them more resistant to penicillinases. Among the cephalosporins which have been found clinically useful are {cephalexin}, {cephaloridine}, and {cephalothin}. [PJC]

The Collaborative International Dictionary of English. 2000.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • Cephalexin — Strukturformel Allgemeines Freiname Cefalexin Andere Namen …   Deutsch Wikipedia

  • cephalexin hydrochloride — [USP] the hydrochloride salt of cephalexin, having the same actions and uses as the base; administered orally …   Medical dictionary

  • cephalexin — noun Etymology: cephalosporin + ex (of unknown origin) + 1 in Date: 1967 a semisynthetic cephalosporin C16H17N3O4S with a spectrum of antibiotic activity similar to the penicillins …   New Collegiate Dictionary

  • cephalexin — /sef euh lek sin/, n. Pharm. an oral, antimicrobial drug, C16H7N3O4S, used in treating minor respiratory and urinary tract infections and as a backup or alternative to penicillin treatment. [1965 70; CEPHAL(OSPORIN) + ex of unclear derivation +… …   Universalium

  • cephalexin — noun A particular oral cephalosporin antibiotic …   Wiktionary

  • cephalexin — A broad spectrum antibiotic derived from cephalosporin C.. * * * ceph·a·lex·in .sef ə lek sən n a semisynthetic cephalosporin C16H17N3O4S with a spectrum of antibiotic activity similar to the penicillins that is often administered in the form of… …   Medical dictionary

  • cephalexin — ceph·a·lex·in …   English syllables

  • cephalexin — An antibiotic drug that belongs to the family of drugs called cephalosporins …   English dictionary of cancer terms

  • cephalexin — noun an oral cephalosporin (trade names Keflex and Keflin and Keftab) commonly prescribe for mild to moderately severe infections of the skin or ears or throat or lungs or urinary tract • Syn: ↑Keflex, ↑Keflin, ↑Keftab • Usage Domain: ↑trade name …   Useful english dictionary

  • Цефалексин (Cephalexin) — антибиотик из группы цефалоспорина; применяется для лечения инфекций дыхательных и мочеполовых путей, инфекционных заболеваний костей и кожи, а также при воспалении среднего уха (отите). Назначается внутрь; наиболее распространенным побочным… …   Медицинские термины

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”